Colours 1 and 2 are fine (here). Colour 3 [Gamboge](https://en.wikipedia.org/wiki/Gamboge) I have already commented on. Note that it depends on what the user brightness setting is for the monitor if it shows as yellow or brown or some orangy colour in between. I forsee much angst from users. Colour 4 does not have sufficient contrast with the background on my Mint-Y-Dark theme, and as the background has a slight green tinge (well its a MINT theme after all) red is a bad contrast for the 10% of males that have reduced red/green colour perception.